Iris Freckles a Potential Biomarker for Chronic Sun Damage
نویسندگان
چکیده
منابع مشابه
Iris Freckles a Potential Biomarker for Chronic Sun Damage.
Purpose To investigate the role of sunlight exposure in iris freckles formation. Methods We prospectively examined volunteers attending a skin cancer screening program conducted by ophthalmologists and dermatologists. Frequency and topographical variability of iris freckles were noted and associated with behavioral and dermatologic characteristics indicating high sun exposure. Results Six h...
متن کاملAssociation between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi.
AIM To investigate the association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi. METHODS Cross sectional study of 65 patients with posterior uveal melanoma and 218 controls. Iris colour, iris freckles, iris naevi, and choroidal naevi were recorded for each eye of each patient. RESULTS Iris freckles were present in 40 (61.5%) patients with melanoma and ...
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Tanning is the increase in skin pigmentmelanin; it causes the change in color of our skin. Excessive tanning causes skin damage. It is overexposure to the UV rays from the sun. The supreme cause of skin cancer is believed to be the over exposure to the solar radiation which is the medley of ultra-violet radiation (UVA, UVB, and UVC), and visible light. UVB is the stronger component amongst the ...
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The renin-angiotensin system is a well-known regulator of blood pressure and plays an important role in the pathogenesis of cardiovascular disease and renal damage. Genetic factors, including single nucleotide polymorphisms and sex, are increasingly recognized as potential risk factors for the development of cardiovascular disease. Double transgenic rats (dTGRs), harboring human renin and angio...
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Concern about intracerebral hemorrhage (ICH) is the primary reason for withholding tPA therapy from patients with ischemic stroke. Early blood brain barrier (BBB) damage is the major risk factor for fatal post-thrombolysis ICH, but rapidly assessing BBB damage before tPA administration is highly challenging. We recently reported that ischemia induced rapid degradation of tight junction protein ...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2017
ISSN: 1552-5783
DOI: 10.1167/iovs.17-21751